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DNA

Assume that in the process of creating a replication bubble during DNA replication, the helicase causes a substitution in the complimentary strand of the DNA it unwound. The mutation was not caught by proof-checking machinery and replication continued. After two rounds of DNA replication, how many strands carry the mutation? Show your thought process
Question asked by: floresj17

Asked on: 20 Oct 2008

There are three strands.

The error is introduced, from what I understand of your wording, in the first replication. So you now have one with the error.

If two more copies of that are now created, then you have two new with errors and the original.

However without knowing the mechanism in place I can't be sure this is the right answer, for instance what form of replication are we talking about - is it 1:1 or 2:1 and are originals destroyed or preserved in the replication? Basically pump in the numbers and do the math.

By: knowitall
Replied at: 02 Nov 2008
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